AustralieFrV1, Main, Exploration, bibRecord, 000494

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Identifieur interne : 000494 ( Main/Exploration ); précédent : 000493; suivant : 000495

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Auteurs : Rohan Sharma ; Valerie M. Harris ; Joshua Cavett ; Biji T. Kurien ; Ke Liu [États-Unis] ; Kristi A. Koelsch ; Anum Fayaaz [États-Unis] ; Kaustubh S. Chaudhari [États-Unis] ; Lida Radfar ; David Lewis ; Donald U. Stone [Arabie saoudite] ; C Erick Kaufman ; Shibo Li ; Barbara Segal ; Daniel J. Wallace [États-Unis] ; Michael H. Weisman [États-Unis] ; Swamy Venuturupalli [États-Unis] ; Jennifer A. Kelly ; Bernardo Pons-Estel [Argentine] ; Roland Jonsson [Norvège] ; Xianglan Lu ; Jacques-Eric Gottenberg [France] ; Juan-Manuel Anaya [Colombie] ; Deborah S. Cunninghame-Graham [Royaume-Uni] ; Andrew J W. Huang ; Michael T. Brennan [États-Unis] ; Pamela Hughes ; Ilias Alevizos [États-Unis] ; Corinne Miceli-Richard [France] ; Edward C. Keystone [Canada] ; Vivian P. Bykerk [États-Unis] ; Gideon Hirschfield [Royaume-Uni] ; Gunnel Nordmark [Suède] ; Sara Magnusson Bucher [Suède] ; Per Eriksson [Suède] ; Roald Omdal [Norvège] ; Nelson L. Rhodus ; Maureen Rischmueller [Australie] ; Michael Rohrer ; Marie Wahren-Herlenius [Suède] ; Torsten Witte [Allemagne] ; Marta Alarc N-Riquelme [Suède] ; Xavier Mariette [France] ; Christopher J. Lessard ; John B. Harley ; Wan-Fai Ng [Royaume-Uni] ; Astrid Rasmussen ; Kathy L. Sivils ; R Hal Scofield

Source :

Arthritis & rheumatology (Hoboken, N.J.) [ 2326-5205 ] ; 2017.

RBID : pubmed:28692793

Descripteurs français

English descriptors

KwdEn :
- Alleles, Bayes Theorem, Chromosomes, Human, X (genetics), Female, Gene Dosage, Humans, Karyotype, Lupus Erythematosus, Systemic (epidemiology), Lupus Erythematosus, Systemic (genetics), Mosaicism (statistics & numerical data), Polymorphism, Single Nucleotide, Sex Chromosome Aberrations (statistics & numerical data), Sex Chromosome Disorders of Sex Development (epidemiology), Sex Chromosome Disorders of Sex Development (genetics), Sjogren's Syndrome (epidemiology), Sjogren's Syndrome (genetics), Trisomy (genetics), Turner Syndrome (epidemiology), Turner Syndrome (genetics).
MESH :
- epidemiology : Lupus Erythematosus, Systemic, Sex Chromosome Disorders of Sex Development, Sjogren's Syndrome, Turner Syndrome.
- genetics : Chromosomes, Human, X, Lupus Erythematosus, Systemic, Sex Chromosome Disorders of Sex Development, Sjogren's Syndrome, Trisomy, Turner Syndrome.
- statistics & numerical data : Mosaicism, Sex Chromosome Aberrations.
- Alleles, Bayes Theorem, Female, Gene Dosage, Humans, Karyotype, Polymorphism, Single Nucleotide.

Abstract

Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are related by clinical and serologic manifestations as well as genetic risks. Both diseases are more commonly found in women than in men, at a ratio of ~10 to 1. Common X chromosome aneuploidies, 47,XXY and 47,XXX, are enriched among men and women, respectively, in either disease, suggesting a dose effect on the X chromosome.

DOI: 10.1002/art.40207
PubMed: 28692793

Affiliations:

Le document en format XML

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<author><name sortKey="Gottenberg, Jacques Eric" sort="Gottenberg, Jacques Eric" uniqKey="Gottenberg J" first="Jacques-Eric" last="Gottenberg">Jacques-Eric Gottenberg</name>
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<author><name sortKey="Brennan, Michael T" sort="Brennan, Michael T" uniqKey="Brennan M" first="Michael T" last="Brennan">Michael T. Brennan</name>
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<author><name sortKey="Alevizos, Ilias" sort="Alevizos, Ilias" uniqKey="Alevizos I" first="Ilias" last="Alevizos">Ilias Alevizos</name>
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<author><name sortKey="Miceli Richard, Corinne" sort="Miceli Richard, Corinne" uniqKey="Miceli Richard C" first="Corinne" last="Miceli-Richard">Corinne Miceli-Richard</name>
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<author><name sortKey="Keystone, Edward C" sort="Keystone, Edward C" uniqKey="Keystone E" first="Edward C" last="Keystone">Edward C. Keystone</name>
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</author>
<author><name sortKey="Nordmark, Gunnel" sort="Nordmark, Gunnel" uniqKey="Nordmark G" first="Gunnel" last="Nordmark">Gunnel Nordmark</name>
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</placeName>
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<author><name sortKey="Bucher, Sara Magnusson" sort="Bucher, Sara Magnusson" uniqKey="Bucher S" first="Sara Magnusson" last="Bucher">Sara Magnusson Bucher</name>
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<author><name sortKey="Eriksson, Per" sort="Eriksson, Per" uniqKey="Eriksson P" first="Per" last="Eriksson">Per Eriksson</name>
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<author><name sortKey="Omdal, Roald" sort="Omdal, Roald" uniqKey="Omdal R" first="Roald" last="Omdal">Roald Omdal</name>
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<author><name sortKey="Rhodus, Nelson L" sort="Rhodus, Nelson L" uniqKey="Rhodus N" first="Nelson L" last="Rhodus">Nelson L. Rhodus</name>
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<author><name sortKey="Rischmueller, Maureen" sort="Rischmueller, Maureen" uniqKey="Rischmueller M" first="Maureen" last="Rischmueller">Maureen Rischmueller</name>
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<author><name sortKey="Rohrer, Michael" sort="Rohrer, Michael" uniqKey="Rohrer M" first="Michael" last="Rohrer">Michael Rohrer</name>
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<author><name sortKey="Wahren Herlenius, Marie" sort="Wahren Herlenius, Marie" uniqKey="Wahren Herlenius M" first="Marie" last="Wahren-Herlenius">Marie Wahren-Herlenius</name>
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<author><name sortKey="Witte, Torsten" sort="Witte, Torsten" uniqKey="Witte T" first="Torsten" last="Witte">Torsten Witte</name>
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<wicri:regionArea>Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Alarc N Riquelme, Marta" sort="Alarc N Riquelme, Marta" uniqKey="Alarc N Riquelme M" first="Marta" last="Alarc N-Riquelme">Marta Alarc N-Riquelme</name>
<affiliation wicri:level="3"><nlm:affiliation>Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain, and Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain, and Karolinska Institutet, Stockholm</wicri:regionArea>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Mariette, Xavier" sort="Mariette, Xavier" uniqKey="Mariette X" first="Xavier" last="Mariette">Xavier Mariette</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre</wicri:regionArea>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Lessard, Christopher J" sort="Lessard, Christopher J" uniqKey="Lessard C" first="Christopher J" last="Lessard">Christopher J. Lessard</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Harley, John B" sort="Harley, John B" uniqKey="Harley J" first="John B" last="Harley">John B. Harley</name>
<affiliation><nlm:affiliation>Cincinnati Children's Hospital Medical Center, University of Cincinnati, and Ohio Department of Veterans Affairs Medical Center, Cincinnati.</nlm:affiliation>
<wicri:noCountry code="subField">Cincinnati</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ng, Wan Fai" sort="Ng, Wan Fai" uniqKey="Ng W" first="Wan-Fai" last="Ng">Wan-Fai Ng</name>
<affiliation wicri:level="1"><nlm:affiliation>Newcastle University, Newcastle upon Tyne, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle University, Newcastle upon Tyne</wicri:regionArea>
<wicri:noRegion>Newcastle upon Tyne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sivils, Kathy L" sort="Sivils, Kathy L" uniqKey="Sivils K" first="Kathy L" last="Sivils">Kathy L. Sivils</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Scofield, R Hal" sort="Scofield, R Hal" uniqKey="Scofield R" first="R Hal" last="Scofield">R Hal Scofield</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Department of Veterans Affairs Medical Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.</title>
<author><name sortKey="Sharma, Rohan" sort="Sharma, Rohan" uniqKey="Sharma R" first="Rohan" last="Sharma">Rohan Sharma</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Department of Veterans Affairs Medical Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Harris, Valerie M" sort="Harris, Valerie M" uniqKey="Harris V" first="Valerie M" last="Harris">Valerie M. Harris</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cavett, Joshua" sort="Cavett, Joshua" uniqKey="Cavett J" first="Joshua" last="Cavett">Joshua Cavett</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kurien, Biji T" sort="Kurien, Biji T" uniqKey="Kurien B" first="Biji T" last="Kurien">Biji T. Kurien</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Department of Veterans Affairs Medical Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Liu, Ke" sort="Liu, Ke" uniqKey="Liu K" first="Ke" last="Liu">Ke Liu</name>
<affiliation wicri:level="2"><nlm:affiliation>Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Ohio</region>
</placeName>
<wicri:cityArea>Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Koelsch, Kristi A" sort="Koelsch, Kristi A" uniqKey="Koelsch K" first="Kristi A" last="Koelsch">Kristi A. Koelsch</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Department of Veterans Affairs Medical Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fayaaz, Anum" sort="Fayaaz, Anum" uniqKey="Fayaaz A" first="Anum" last="Fayaaz">Anum Fayaaz</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Oklahoma</region>
</placeName>
<wicri:cityArea>Department of Veterans Affairs Medical Center, Oklahoma City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Chaudhari, Kaustubh S" sort="Chaudhari, Kaustubh S" uniqKey="Chaudhari K" first="Kaustubh S" last="Chaudhari">Kaustubh S. Chaudhari</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Oklahoma</region>
</placeName>
<wicri:cityArea>Department of Veterans Affairs Medical Center, Oklahoma City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Radfar, Lida" sort="Radfar, Lida" uniqKey="Radfar L" first="Lida" last="Radfar">Lida Radfar</name>
<affiliation><nlm:affiliation>University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lewis, David" sort="Lewis, David" uniqKey="Lewis D" first="David" last="Lewis">David Lewis</name>
<affiliation><nlm:affiliation>University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Stone, Donald U" sort="Stone, Donald U" uniqKey="Stone D" first="Donald U" last="Stone">Donald U. Stone</name>
<affiliation wicri:level="1"><nlm:affiliation>Johns Hopkins University, Baltimore, Maryland, and King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Johns Hopkins University, Baltimore, Maryland, and King Khaled Eye Specialist Hospital, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kaufman, C Erick" sort="Kaufman, C Erick" uniqKey="Kaufman C" first="C Erick" last="Kaufman">C Erick Kaufman</name>
<affiliation><nlm:affiliation>University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Li, Shibo" sort="Li, Shibo" uniqKey="Li S" first="Shibo" last="Li">Shibo Li</name>
<affiliation><nlm:affiliation>University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Segal, Barbara" sort="Segal, Barbara" uniqKey="Segal B" first="Barbara" last="Segal">Barbara Segal</name>
<affiliation><nlm:affiliation>University of Minnesota Medical School, Minneapolis.</nlm:affiliation>
<wicri:noCountry code="subField">Minneapolis</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wallace, Daniel J" sort="Wallace, Daniel J" uniqKey="Wallace D" first="Daniel J" last="Wallace">Daniel J. Wallace</name>
<affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Cedars-Sinai Medical Center, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Weisman, Michael H" sort="Weisman, Michael H" uniqKey="Weisman M" first="Michael H" last="Weisman">Michael H. Weisman</name>
<affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Cedars-Sinai Medical Center, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Venuturupalli, Swamy" sort="Venuturupalli, Swamy" uniqKey="Venuturupalli S" first="Swamy" last="Venuturupalli">Swamy Venuturupalli</name>
<affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Cedars-Sinai Medical Center, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kelly, Jennifer A" sort="Kelly, Jennifer A" uniqKey="Kelly J" first="Jennifer A" last="Kelly">Jennifer A. Kelly</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pons Estel, Bernardo" sort="Pons Estel, Bernardo" uniqKey="Pons Estel B" first="Bernardo" last="Pons-Estel">Bernardo Pons-Estel</name>
<affiliation wicri:level="1"><nlm:affiliation>Sanatorio Parque, Rosario, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Sanatorio Parque, Rosario</wicri:regionArea>
<wicri:noRegion>Rosario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jonsson, Roland" sort="Jonsson, Roland" uniqKey="Jonsson R" first="Roland" last="Jonsson">Roland Jonsson</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Bergen and Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>University of Bergen and Haukeland University Hospital, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lu, Xianglan" sort="Lu, Xianglan" uniqKey="Lu X" first="Xianglan" last="Lu">Xianglan Lu</name>
<affiliation><nlm:affiliation>University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gottenberg, Jacques Eric" sort="Gottenberg, Jacques Eric" uniqKey="Gottenberg J" first="Jacques-Eric" last="Gottenberg">Jacques-Eric Gottenberg</name>
<affiliation wicri:level="3"><nlm:affiliation>Strasbourg University, Strasbourg, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Strasbourg University, Strasbourg</wicri:regionArea>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Anaya, Juan Manuel" sort="Anaya, Juan Manuel" uniqKey="Anaya J" first="Juan-Manuel" last="Anaya">Juan-Manuel Anaya</name>
<affiliation wicri:level="1"><nlm:affiliation>Universidad del Rosario, Bogota, Colombia.</nlm:affiliation>
<country xml:lang="fr">Colombie</country>
<wicri:regionArea>Universidad del Rosario, Bogota</wicri:regionArea>
<wicri:noRegion>Bogota</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cunninghame Graham, Deborah S" sort="Cunninghame Graham, Deborah S" uniqKey="Cunninghame Graham D" first="Deborah S" last="Cunninghame-Graham">Deborah S. Cunninghame-Graham</name>
<affiliation wicri:level="3"><nlm:affiliation>King's College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>King's College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huang, Andrew J W" sort="Huang, Andrew J W" uniqKey="Huang A" first="Andrew J W" last="Huang">Andrew J W. Huang</name>
<affiliation><nlm:affiliation>University of Minnesota, Minneapolis.</nlm:affiliation>
<wicri:noCountry code="subField">Minneapolis</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Brennan, Michael T" sort="Brennan, Michael T" uniqKey="Brennan M" first="Michael T" last="Brennan">Michael T. Brennan</name>
<affiliation wicri:level="2"><nlm:affiliation>Carolinas Medical Center, Charlotte, North Carolina.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>Carolinas Medical Center, Charlotte</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hughes, Pamela" sort="Hughes, Pamela" uniqKey="Hughes P" first="Pamela" last="Hughes">Pamela Hughes</name>
<affiliation><nlm:affiliation>University of Minnesota, Minneapolis.</nlm:affiliation>
<wicri:noCountry code="subField">Minneapolis</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Alevizos, Ilias" sort="Alevizos, Ilias" uniqKey="Alevizos I" first="Ilias" last="Alevizos">Ilias Alevizos</name>
<affiliation wicri:level="2"><nlm:affiliation>National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>National Institute of Dental and Craniofacial Research, NIH, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Miceli Richard, Corinne" sort="Miceli Richard, Corinne" uniqKey="Miceli Richard C" first="Corinne" last="Miceli-Richard">Corinne Miceli-Richard</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre</wicri:regionArea>
<wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion>
<orgName type="university">Université Paris-Sud</orgName>
<placeName><settlement type="city">Orsay</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Keystone, Edward C" sort="Keystone, Edward C" uniqKey="Keystone E" first="Edward C" last="Keystone">Edward C. Keystone</name>
<affiliation wicri:level="4"><nlm:affiliation>Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Mount Sinai Hospital and University of Toronto, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bykerk, Vivian P" sort="Bykerk, Vivian P" uniqKey="Bykerk V" first="Vivian P" last="Bykerk">Vivian P. Bykerk</name>
<affiliation wicri:level="2"><nlm:affiliation>Hospital for Special Surgery, New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Hospital for Special Surgery, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hirschfield, Gideon" sort="Hirschfield, Gideon" uniqKey="Hirschfield G" first="Gideon" last="Hirschfield">Gideon Hirschfield</name>
<affiliation wicri:level="4"><nlm:affiliation>University of Birmingham, Birmingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of Birmingham, Birmingham</wicri:regionArea>
<placeName><settlement type="city">Birmingham</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Midlands de l'Ouest</region>
<settlement type="city">Birmingham</settlement>
</placeName>
<orgName type="university">Université de Birmingham</orgName>
</affiliation>
</author>
<author><name sortKey="Nordmark, Gunnel" sort="Nordmark, Gunnel" uniqKey="Nordmark G" first="Gunnel" last="Nordmark">Gunnel Nordmark</name>
<affiliation wicri:level="4"><nlm:affiliation>Uppsala University, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName><settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bucher, Sara Magnusson" sort="Bucher, Sara Magnusson" uniqKey="Bucher S" first="Sara Magnusson" last="Bucher">Sara Magnusson Bucher</name>
<affiliation wicri:level="1"><nlm:affiliation>Örebro University Hospital, Örebro, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Örebro University Hospital, Örebro</wicri:regionArea>
<wicri:noRegion>Örebro</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Eriksson, Per" sort="Eriksson, Per" uniqKey="Eriksson P" first="Per" last="Eriksson">Per Eriksson</name>
<affiliation wicri:level="1"><nlm:affiliation>Linköping University, Linköping, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Linköping University, Linköping</wicri:regionArea>
<wicri:noRegion>Linköping</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Omdal, Roald" sort="Omdal, Roald" uniqKey="Omdal R" first="Roald" last="Omdal">Roald Omdal</name>
<affiliation wicri:level="1"><nlm:affiliation>Stavanger University Hospital, Stavanger, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Stavanger University Hospital, Stavanger</wicri:regionArea>
<wicri:noRegion>Stavanger</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rhodus, Nelson L" sort="Rhodus, Nelson L" uniqKey="Rhodus N" first="Nelson L" last="Rhodus">Nelson L. Rhodus</name>
<affiliation><nlm:affiliation>University of Minnesota, Minneapolis.</nlm:affiliation>
<wicri:noCountry code="subField">Minneapolis</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rischmueller, Maureen" sort="Rischmueller, Maureen" uniqKey="Rischmueller M" first="Maureen" last="Rischmueller">Maureen Rischmueller</name>
<affiliation wicri:level="1"><nlm:affiliation>The Queen Elizabeth Hospital, Woodville South, and University of Adelaide, Adelaide, South Australia, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The Queen Elizabeth Hospital, Woodville South, and University of Adelaide, Adelaide, South Australia</wicri:regionArea>
<wicri:noRegion>South Australia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rohrer, Michael" sort="Rohrer, Michael" uniqKey="Rohrer M" first="Michael" last="Rohrer">Michael Rohrer</name>
<affiliation><nlm:affiliation>University of Minnesota, Minneapolis.</nlm:affiliation>
<wicri:noCountry code="subField">Minneapolis</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wahren Herlenius, Marie" sort="Wahren Herlenius, Marie" uniqKey="Wahren Herlenius M" first="Marie" last="Wahren-Herlenius">Marie Wahren-Herlenius</name>
<affiliation wicri:level="3"><nlm:affiliation>Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Witte, Torsten" sort="Witte, Torsten" uniqKey="Witte T" first="Torsten" last="Witte">Torsten Witte</name>
<affiliation wicri:level="3"><nlm:affiliation>Hannover Medical School, Hannover, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alarc N Riquelme, Marta" sort="Alarc N Riquelme, Marta" uniqKey="Alarc N Riquelme M" first="Marta" last="Alarc N-Riquelme">Marta Alarc N-Riquelme</name>
<affiliation wicri:level="3"><nlm:affiliation>Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain, and Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain, and Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mariette, Xavier" sort="Mariette, Xavier" uniqKey="Mariette X" first="Xavier" last="Mariette">Xavier Mariette</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Rheumatology, Université Paris-Sud, AP-HP, INSERM U1012, Le Kremlin-Bicêtre</wicri:regionArea>
<wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion>
<orgName type="university">Université Paris-Sud</orgName>
<placeName><settlement type="city">Orsay</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lessard, Christopher J" sort="Lessard, Christopher J" uniqKey="Lessard C" first="Christopher J" last="Lessard">Christopher J. Lessard</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Harley, John B" sort="Harley, John B" uniqKey="Harley J" first="John B" last="Harley">John B. Harley</name>
<affiliation><nlm:affiliation>Cincinnati Children's Hospital Medical Center, University of Cincinnati, and Ohio Department of Veterans Affairs Medical Center, Cincinnati.</nlm:affiliation>
<wicri:noCountry code="subField">Cincinnati</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ng, Wan Fai" sort="Ng, Wan Fai" uniqKey="Ng W" first="Wan-Fai" last="Ng">Wan-Fai Ng</name>
<affiliation wicri:level="1"><nlm:affiliation>Newcastle University, Newcastle upon Tyne, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle University, Newcastle upon Tyne</wicri:regionArea>
<wicri:noRegion>Newcastle upon Tyne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sivils, Kathy L" sort="Sivils, Kathy L" uniqKey="Sivils K" first="Kathy L" last="Sivils">Kathy L. Sivils</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Scofield, R Hal" sort="Scofield, R Hal" uniqKey="Scofield R" first="R Hal" last="Scofield">R Hal Scofield</name>
<affiliation><nlm:affiliation>Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Department of Veterans Affairs Medical Center, Oklahoma City.</nlm:affiliation>
<wicri:noCountry code="subField">Oklahoma City</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">Arthritis & rheumatology (Hoboken, N.J.)</title>
<idno type="eISSN">2326-5205</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alleles</term>
<term>Bayes Theorem</term>
<term>Chromosomes, Human, X (genetics)</term>
<term>Female</term>
<term>Gene Dosage</term>
<term>Humans</term>
<term>Karyotype</term>
<term>Lupus Erythematosus, Systemic (epidemiology)</term>
<term>Lupus Erythematosus, Systemic (genetics)</term>
<term>Mosaicism (statistics & numerical data)</term>
<term>Polymorphism, Single Nucleotide</term>
<term>Sex Chromosome Aberrations (statistics & numerical data)</term>
<term>Sex Chromosome Disorders of Sex Development (epidemiology)</term>
<term>Sex Chromosome Disorders of Sex Development (genetics)</term>
<term>Sjogren's Syndrome (epidemiology)</term>
<term>Sjogren's Syndrome (genetics)</term>
<term>Trisomy (genetics)</term>
<term>Turner Syndrome (epidemiology)</term>
<term>Turner Syndrome (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Aberrations des chromosomes sexuels ()</term>
<term>Allèles</term>
<term>Caryotype</term>
<term>Chromosomes X humains (génétique)</term>
<term>Dosage génique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lupus érythémateux disséminé (génétique)</term>
<term>Lupus érythémateux disséminé (épidémiologie)</term>
<term>Mosaïcisme ()</term>
<term>Polymorphisme de nucléotide simple</term>
<term>Syndrome de Gougerot-Sjögren (génétique)</term>
<term>Syndrome de Gougerot-Sjögren (épidémiologie)</term>
<term>Syndrome de Turner (génétique)</term>
<term>Syndrome de Turner (épidémiologie)</term>
<term>Théorème de Bayes</term>
<term>Trisomie (génétique)</term>
<term>Troubles du développement sexuel avec anomalie des gonosomes (génétique)</term>
<term>Troubles du développement sexuel avec anomalie des gonosomes (épidémiologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Lupus Erythematosus, Systemic</term>
<term>Sex Chromosome Disorders of Sex Development</term>
<term>Sjogren's Syndrome</term>
<term>Turner Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Chromosomes, Human, X</term>
<term>Lupus Erythematosus, Systemic</term>
<term>Sex Chromosome Disorders of Sex Development</term>
<term>Sjogren's Syndrome</term>
<term>Trisomy</term>
<term>Turner Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Chromosomes X humains</term>
<term>Lupus érythémateux disséminé</term>
<term>Syndrome de Gougerot-Sjögren</term>
<term>Syndrome de Turner</term>
<term>Trisomie</term>
<term>Troubles du développement sexuel avec anomalie des gonosomes</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Mosaicism</term>
<term>Sex Chromosome Aberrations</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Lupus érythémateux disséminé</term>
<term>Syndrome de Gougerot-Sjögren</term>
<term>Syndrome de Turner</term>
<term>Troubles du développement sexuel avec anomalie des gonosomes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Alleles</term>
<term>Bayes Theorem</term>
<term>Female</term>
<term>Gene Dosage</term>
<term>Humans</term>
<term>Karyotype</term>
<term>Polymorphism, Single Nucleotide</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Aberrations des chromosomes sexuels</term>
<term>Allèles</term>
<term>Caryotype</term>
<term>Dosage génique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mosaïcisme</term>
<term>Polymorphisme de nucléotide simple</term>
<term>Théorème de Bayes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are related by clinical and serologic manifestations as well as genetic risks. Both diseases are more commonly found in women than in men, at a ratio of ~10 to 1. Common X chromosome aneuploidies, 47,XXY and 47,XXX, are enriched among men and women, respectively, in either disease, suggesting a dose effect on the X chromosome.</div>
</front>
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<name sortKey="Weisman, Michael H" sort="Weisman, Michael H" uniqKey="Weisman M" first="Michael H" last="Weisman">Michael H. Weisman</name>
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Serveur d'exploration sur les relations entre la France et l'Australie

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.

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